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Adding Variety to the Top Set/Back-Off Set Method

 by on October 24, 2025

Over the last several years, the concept of using a top set and back-off set instead of a conventional “3 sets of 10” volume approach has risen significantly in popularity – you can find this method used frequently in programs like Cris Edmonds’ new Scorpion and Sub-Zero programs, and many other well-regarded bodybuilding coaches like the Hypertrophy Coach Joe Bennett cite it frequently in their work as well.

SLU-PP-332: Is it really an exercise mimetic?

 by on March 31, 2025

SLU-PP-332 is a synthetic compound that functions as a pan-agonist (a drug or compound that activates multiple subtypes of a specific receptor) for estrogen receptor-related receptors (ERRs), particularly ERRα. It has been shown to enhance mitochondrial function and respiration in skeletal muscle cells, effectively mimicking the same effects one would get from physical exercise. This has made it a promising candidate for therapeutic interventions in metabolic diseases, muscle disorders and of course physique enhancement.